A drug inhibits SERCA pumps in skeletal muscle. Which out...

A drug inhibits SERCA pumps in skeletal muscle. Which outcome is most likely?

hard

AFaster relaxation because Ca2+ is removed more quickly

Slower relaxation and prolonged contraction because cytosolic Ca2+ stays high

CNo change because SERCA is not involved in Ca2+ handling

DImmediate breakdown of actin filaments

EMore acetylcholine release at the neuromuscular junction

Explanation

If Ca2+ cannot be pumped back into the SR, it remains in the cytosol longer, keeping troponin activated and delaying relaxation.

Source: entermedschool.org