Hodgkin lymphoma

B‑cell lymphoma characterized by Reed–Sternberg (CD15+, CD30+) cells and contiguous nodal spread.

• Classically presents with B symptoms; highly curable with stage‑based therapy.

• Painless cervical/mediastinal nodes in a young adult
• Alcohol‑induced node pain (classic exam tidbit)

1. Look for contiguous spread pattern; RS cells on histology
2. Check for EBV association; define subtype (e.g., nodular sclerosis)

1. ABVD‑based regimens; involved‑field radiation depending on stage

• RS cells = 'owl‑eye' nucleoli; CD15/CD30 positive
• Pruritus and Pel‑Ebstein fevers sometimes tested

• Mediastinal mass + B symptoms in young woman (nodular sclerosis)